Liverpool will take on a Serie A side for the second consecutive matchday in the Champions League, having previously triumphed over AC Milan during their visit to San Siro last month.
This time, Bologna are the visitors to Anfield, having surprised everyone last season by finishing fifth in Italy, which secured their spot in the European Cup for the first time since 1964.
However, their opening game against Shakhtar Donetsk ended in a goalless draw.
Meanwhile, Liverpool currently sit at the summit of the Premier League table following the latest round of fixtures over the weekend.
Aside from a minor setback against Nottingham Forest, they are thriving under manager Arne Slot.
Speaking ahead of the game, Slot said: “I think Bologna showed last season and this season again that they are a real difficult team to beat because everybody is telling me they only won once, but I‘ll tell everyone they only lost once.
“That means it‘s a difficult team to beat and we as Liverpool know how difficult it can be to play against a team that‘s man-marking all over the pitch, which is what Bologna does, and what Atalanta did here last season.
“To face an Italian team at Champions League level, we know how difficult it was to face an Italian team on Europa League level, so we don‘t underestimate them at all.
“That‘s also not what they deserve for the way they played last season and even this season.
He added: “One of the reasons we can compete is because we have a lot of quality and I also see a lot of team cohesion in the team.
“So, if we score, I also see the ones who don’t play are really happy with us scoring [and] with us winning.
“Those are two really positive things, but I also see things we definitely have to improve if we want to stay where we are with the fixture list coming up.
“Like I said, every fixture [is] really difficult in the Premier League, but everybody tells me that a top league table team is a bit more difficult than a lower league table team, which we can all understand, and we haven’t faced one of them yet.
“So, we have to do things better, but one of the reasons why we can stay up there is because we have a lot of players with a lot of individual quality.”
Liverpool: Alisson; Alexander-Arnold, Konate, Van Dijk, Robertson; Gravenberch, Szoboszlai, Mac Allister; Salah, Nunez, Diaz.
Subs: Jaros, Kelleher, Gomez, Endo, Jones, Gakpo, Jota, Tsimikas, Quansah, Morton, Bradley, Nyoni.
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